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TIGAN® (trimethobenzamide HCl) Adverse Reactions


The following adverse reactions from voluntary reports or clinical studies have been reported with trimethobenzamide. Because many of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

  • Nervous system disorders: Parkinson-like symptoms, coma, convulsions, opisthotonos, dizziness, drowsiness, headache, [see Warnings and Precautions (5.1, 5.2, 5.3)]
  • Psychiatric disorders: disorientation, depression of mood
  • Eye disorders: blurred vision
  • Hematologic disorders: blood dyscrasias
  • Hepatobiliary disorders: jaundice [see Warnings and Precautions (5.4)]
  • Immune system disorders: hypersensitivity, including angioedema and allergic-type skin reactions
  • Gastrointestinal disorders: diarrhea
  • Musculoskeletal disorders: muscle cramps
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